Completely pulsatile high flow circulatory support with a constant-speed centrifugal blood pump: mechanisms and early clinical observations.
نویسندگان
چکیده
OBJECTIVE Various types of rotary blood pumps (axial flow, centrifugal) have been introduced into clinical use recently. These pumps have different pressure-flow characteristics, and some investigators have noted that a limited pump flow rate and less pulsatility are the problems with the axial flow devices. METHODS A new implantable centrifugal blood pump was developed that has an extremely flat pressure-flow curve and is able to produce a significantly high pump flow rate of 20 l/min at a low pressure of 10-30mmHg. When the pressure difference between the left ventricle and aorta decreases during systole, an instant high peak flow is achieved, which results in a higher peak pressure in the aorta (systolic pressure). During the diastolic phase, the left ventricle-aorta pressure difference increases to maximum, and the pump flow rate decreases to minimum. Thus, the pump flow rate becomes completely pulsatile, and the high peak flow provides a higher mean pump flow rate. This pump was applied to two end-stage heart failure patients (dilated cardiomyopathy, New York Heart Association (NYHA) class IV, inotrope-dependent). RESULTS The pump was observed to provide completely pulsatile high flow assistance of 6-9 l/min with a constant pump speed. Both patients are currently in NYHA class I after 1 year on the device with no major adverse events. CONCLUSION The new centrifugal blood pump provides completely pulsatile high-flow circulatory support with a constant pump speed, which solves the current clinical problems with rotary blood pumps.
منابع مشابه
Impeller and volute design and optimization of the centrifugal pump with low specific speed in order to extract performance curves
Now a day centrifugal pumps are vital components of industries. Certainly, one of the most important specifications of centrifugal pumps are the performance curves. In the present work, performance curves of a centrifugal pumps are obtained by Computational fluid dynamics (CFD) and as an outcome, CFD results compare by practical curves. At the first step impeller and volute are designed with tw...
متن کاملA mathematical model to evaluate control strategies for mechanical circulatory support.
Continuous flow ventricular assist devices (VADs) for mechanical circulatory support (MCS) are generally smaller and believed to be more reliable than pulsatile VADs. However, regarding continuous flow, there are concerns about the decreased pulsatility and ventricular unloading. Moreover, pulsatile VADs offer a wider range in control strategies. For this reason, we used a computer model to eva...
متن کاملEnhancement of Arterial Pressure Pulsatility by Controlling Continuous-Flow Left Ventricular Assist Device Flow Rate in Mock Circulatory System
Continuous-flow left ventricular assist devices (CF-LVADs) generally operate at a constant speed, which reduces pulsatility in the arteries and may lead to complications such as functional changes in the vascular system, gastrointestinal bleeding, or both. The purpose of this study is to increase the arterial pulse pressure and pulsatility by controlling the CF-LVAD flow rate. A MicroMed DeBake...
متن کاملMethod of Evaluation of Efficiency Improvement Potential for District Heating Systems with Focus on Variable Speed Centrifugal Pumps
The goal of this research is the derivation of method for evaluation of efficiency improvement potential for district heating systems with focus on variable speed centrifugal pump. The effectiveness of the usage of the proportional pressure control is compared with the constant pressure control. This is why, energy calculation analyses have been realized for variable speed centrifugal pumps, an...
متن کاملAn Implantable Ventricular Assist System Employing a Radially Controlled Maglev Centrifugal Blood Pump with Capability to Measure Blood Flow Rate without Additional Sensors
In order to solve the problems of lack of heart donors for transplant, implantable ventricular assist systems (VAS) have been developed to assist the failing heart ventricle. One of the components of a VAS is a blood pump that connects the left ventricle to the aorta. Therefore, the pump flow rate is influenced by the cardio-vascular system. To control the flow rate through the blood pump, real...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- General thoracic and cardiovascular surgery
دوره 55 4 شماره
صفحات -
تاریخ انتشار 2007